Biotechnology & Genetics — UPSC Prelims Previous Year Questions
53 questions from UPSC CSE Prelims GS Paper 1 on Biotechnology & Genetics (Science & Technology). Spanning from 1996 to 2025. Practice with show/hide answers and detailed explanations.
Based on 53 questions across 24 years, UPSC has consistently tested aspirants' understanding of Biotechnology & Genetics within the broader Science & Technology syllabus. The questions range from factual recall to application-based analysis.
Recent trends show UPSC moving towards statement-based questions that combine multiple aspects of Biotechnology & Genetics. Aspirants should focus on understanding concepts rather than memorizing isolated facts.
Q: With reference to monoclonal antibodies, often mentioned in news, consider the following statements:
I. They are man-made proteins.
II. They stimulate immunological function due to their ability to bind to specific antigens.
III. They are used in treating viral infections like that of Nipah virus.
Which of the statements given above are correct?
Q: Consider the following statements:
DNA Barcoding can be a tool to:
1. assess the age of a plant or animal.
2. distinguish among species that look alike.
3. identify undesirable animal or plant materials in processed foods.
Which of the statements given above is/are correct?
Q: With reference to recent developments regarding 'Recombinant Vector Vaccines', consider the following statements:
1. Genetic engineering is applied in the development of these vaccines.
2. Bacteria and viruses are used as vectors.
Which of the statements given above is/are correct?
Q: In the context of hereditary diseases, consider the following statements:
1. Passing on mitochondrial diseases from parent to child can be prevented by mitochondrial replacement therapy either before or after in vitro fertilization of egg.
2. A child inherits mitochondrial diseases entirely from mother and not from father.
Which of the statements given above is/are correct?
Q: Consider the following statements :
1. Genetic changes can be introduced in the cells that produce eggs or sperms of a prospective parent.
2. A person’s genome can be edited before birth at the early embryonic stage.
3. Human induced pluripotent stem cells can be injected into the embryo of a pig.
Which of the statements given above is/are correct ?
Q: 'RNA interference (RNAi) technology has gained popularity in the last few years. Why?
1. It is used in developing gene silencing therapies.
2. It can be used in developing therapies for the treatment of cancer.
3. It can be used to develop hormone replacement therapies.
4. It can be used to produce crop plants that are resistant to viral pathogens.
Select the correct answer using the code given below.
Q: भारत में विकसित आनुवंशिकतः संशोधित सरसों (जेनेटिकली मॉडिफाइड सरसों / GM सरसों) के सन्दर्भ में, निम्नलिखित कथनों पर विचार कीजिए:
1. GM सरसों में सूक्ष्म जीवाणु के जीन्स होते हैं जो पौध को अनेक किस्मों के कीटकों के विरुद्ध प्रतिरोधी बना देते हैं।
2. GM सरसों में वे जीन्स होते हैं जो पौध में पर-परागण को सुकर बनाते हैं।
3. GM सरसों का विकास IARI और पंजाब कृषि विश्वविद्यालय द्वारा संयुक्त रूप से किया गया है।
उपरोक्त कथनों में से कौन-सा/से सही है/हैं?
Q: With reference to agriculture in India, how can the technique of 'genome sequencing', often seen in the news, be used in the immediate future?
1. Genome sequencing can be used to identify genetic markers for disease resistance and drought tolerance in various crop plants.
2. This technique helps in reducing the time required to develop new varieties of crop plants.
3. It can be used to decipher the host-pathogen relationships in crops.
Select the correct answer using the code given below:
Q: With reference to bio-toilets used by the Indian Railways, consider the following statements:
1. The decomposition of human waste in the bio-toilets is initiated by a fungal inoculum.
2. Ammonia and water vapour are the only end products in this decomposition which are released into the atmosphere.
Which of the statements given above is/are correct?
Q: Which of the following statements is/are correct regarding vegetative propagation of plants?
1. Vegetative propagation produces clonal population.
2. Vegetative propagation helps in eliminating the virus.
3. Vegetative propagation can be practiced most of the year.
Select the correct answer using the code given below.
Q: Consider the following techniques/phenomena :
1. Budding and grafting in fruit plants
2. Cytoplasmic male sterility
3. Gene silencing
Which of the above is/are used to create transgenic crops?
Q: Recombinant DNA technology (Genetic Engineering) allows genes to be transferred
1. across different species of plants
2. from animals to plants
3. from microorganisms to higher organisms
Select the correct answer using the codes given below.
Q: With reference to 'stem cells', frequently in the news, which of the following statements is/are correct?
1. Stem cells can be derived from mammals only.
2. Stem cells can be used for screening new drugs.
3. Stem cells can be used for medical therapies.
Q: At present, scientists can determine the arrangement or relative positions of genes or DNA sequences on a chromosome. How does this knowledge benefit us?
1. It is possible to know the pedigree of livestock.
2. It is possible to understand the causes of all human diseases.
3. It is possible to develop disease-resistant animal breeds.
Which of the statements given above is/are correct?
Q: A married couple adopted a male child. A few years later twin boys were born to them. The blood group of the couple is AB positive and O negative. The blood group of the three sons is A positive, B positive, and O positive. The blood group of the adopted son is
(a)O positive
(b)A positive
(c)B positive
(d)Cannot be determined on the basis of the given data
Q: Genetically modified “golden rice” has been engineered to meet human nutritional requirements. Which one of the following statements best qualifies golden rice?
(a)The grains have been fortified with genes to provide three times higher grain yield per acre than other high yielding varieties
(b)Its grains contain pro-vitamin A which upon ingestion is converted to vitamin A in the human body
(c)Its modified genes cause the synthesis of all the nine essential amino acids
(d)Its modified genes cause the fortification of its grains with vitamin D
Q: In the context of genetic disorders, consider the following:
A woman suffers from colour blindness while her husband does not suffer from it. They have a son and a daughter. In this context, which one of the following statements is most probably correct ?
(a)Both children suffer from colour blindness
(b)Daughter suffers from colour blindness while son does not suffer from it
(c)Both children do not suffer from colour blindness
(d)Son suffers from colour blindness while daughter does not suffer from it
Q: With reference to the latest developments in stem-cell research, consider the following statements:
1. The only source of human stem cells are the embryos at blastocyst stage.
2. The stem cells can be derived without causing destruction to blastocysts.
3. The stem cells can regenerate themselves in vitro virtually forever.
4. Indian research centres also created a few cell lines which can be developed into many types of tissues.
Which of these statements are correct?
Q: Assertion (A): Scientists can cut apart and paste together DNA molecules at will, regardless of the source of the molecules.
Reason (R): DNA fragments can be manipulated using restriction endonucleases and DNA ligases.
Which of the following is correct?
(a)Both A and R are individually true and R is the correct explanation of A
(b)Both A and R are individually true but R is NOT a correct explanation of A
Q: The American multinational company, Monsanto has produced an insect-resistant cotton variety that is undergoing field-trials in India. A toxin gene from which ONE of the following bacteria has been transferred to this transgenic cotton?
Q: Assertion (A): “DNA Finger-printing” has become a powerful tool to establish paternity and identity of criminals in rape and assault cases.
Reason (R): Trace evidences such as hairs, saliva and dried semen are adequate for DNA analysis.
(a)Both A and R are true, and R is the correct explanation of A
(b)Both A and R are true, but R is not a correct explanation of A
Q: Which of the following professional(s) are more likely to run the risk of a permanent change in their cell’s DNA?
I. Researchers using carbon-14 isotope
II. X-ray technician
III. Coal miner
IV. Dyer and painter
Select the correct answer using the codes given below:
Q: It is possible to produce seedless tomato fruits by
(a)applying trace elements in tomato fields
(b)spraying mineral solution on plants
(c)spraying hormones on flowers
(d)applying fertilisers containing radioactive elements
Frequently Asked Questions
How many UPSC Prelims questions have been asked from Biotechnology & Genetics?▼
UPSC has asked 53 questions on Biotechnology & Genetics in GS Paper 1 Prelims between 1996 and 2025. This sub-topic falls under Science & Technology.
In which years has UPSC asked about Biotechnology & Genetics?▼
Questions on Biotechnology & Genetics have appeared in UPSC Prelims in the following years: 2025, 2024, 2023, 2022, 2021, 2020, 2019, 2018, 2017, 2016, 2015, 2014, 2013, 2012, 2011, 2010, 2009, 2002, 2001, 2000, 1999, 1998, 1997, 1996. The topic has appeared in 24 out of 31 years.
What is the difficulty level of Biotechnology & Genetics questions in UPSC Prelims?▼
Among 53 questions on Biotechnology & Genetics: 24 are easy, 27 are moderate, and 2 are difficult. Most questions test conceptual understanding of the topic.