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UPSC 2020: In the context of recent advances in human reproductive technology, “Pronuclear Transfer” is used for
(a)fertilization of egg in vitro by the donor sperm
(b)genetic modification of sperm producing cells
(c)development of stem cells into functional embryos"
(d)prevention of mitochondrial diseases in offspring
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Not attemptedCorrect Answer: (d) prevention of mitochondrial diseases in offspring
Pronuclear transfer replaces the parents’ pronuclei into a donor zygote with healthy mitochondria, creating a “three-parent” embryo that prevents mitochondrial DNA disorders from being passed to the child. It is not used for donor sperm IVF, nuclear transfer to sperm-forming cells, or stem-cell tissue engineering. ([theguardian.com](https://www.theguardian.com/science/2015/feb/02/three-parent-babies-explained?utm_source=openai))
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Frequently Asked Questions
What is the correct answer to this UPSC 2020 Science & Technology question?▼
The correct answer is option (d): prevention of mitochondrial diseases in offspring. Watch the detailed video explanation in our Sherlocking Prelims course on UnlockIAS.
Which year was this Biotechnology & Genetics question asked in UPSC Prelims?▼
This question was asked in UPSC CSE Prelims 2020, GS Paper 1, as Question 37. It falls under Science & Technology > Biotechnology & Genetics.
What is the difficulty level of this UPSC question?▼
This question is rated "moderate". It requires sound conceptual understanding of the topic.
How many UPSC Prelims questions have been asked from Biotechnology & Genetics?▼
UPSC has asked 54 questions from Biotechnology & Genetics (under Science & Technology) across multiple years. Visit the topic page to see the full list and year-wise trends.