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Sherlocking Revision Doc — Science & Technology 2024
Comprehensive Science & Technology revision notes for UPSC Prelims covering Genome Editing, Quantum Technology, Space Technology (ISRO, Chandrayaan-3), Defence Systems, Health & Pharma, Nuclear Energy, and more — organized for quick revision.
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Sherlocking Revision — S&T 2024 (Complete PDF)(23 MB)
Practice Science & Technology questions with the Sherlocking Method
Attempt UPSC-level MCQs with detailed explanations and smart elimination strategies.
- Indian researchers developed first low-pungent mustard using CRISPR/Cas9 on Varuna variety (Brassica juncea)
- Genome Editing uses site directed nucleases (SDNs); SDN1 and SDN2 do not involve alien genetic material; SDN3 involves foreign genes
- Bt cotton: only GM crop approved for commercial cultivation in India; Cry2Ai gene for pink bollworm resistance
- Dhara Mustard Hybrid-11 (DMH-11): developed by Delhi University using Recombinant DNA technology
- Gene-Drive Technology (GDT): modifies genes to alter Mendelian inheritance; promising for mosquito population reduction
- Human Genome Project: launched 1990, completed 2003, covered 92% of total genome; IndiGen programme sequenced 1029 Indians
- Three Parent Baby: Mitochondrial Donation Treatment (MDT) — Maternal Spindle Transfer and Pronuclear Transfer techniques
- Stem Cells: unique ability to develop into specialized cell types; autologous (own) vs allogenic (donor) transplantation
- CAR-T Cell Therapy: genetically altered T cells to attack cancer; CD-19 is biomarker for B lymphocytes
Download the full PDF
Sherlocking Revision — S&T 2024 (Complete PDF)(23 MB)
Practice Science & Technology questions with the Sherlocking Method
Attempt UPSC-level MCQs with detailed explanations and smart elimination strategies.