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Sherlocking Revision Doc — Science & Technology 2023
Science & Technology revision notes for UPSC Prelims 2023 covering Genome Editing, GEAC, CAR-T Therapy, AI & Blockchain, ISRO Launch Vehicles, Defence Technology, Green Hydrogen Mission, and more — organized for quick revision.
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Sherlocking Revision — S&T 2023 (Complete PDF)(2.5 MB)
Practice Science & Technology questions with the Sherlocking Method
Attempt UPSC-level MCQs with detailed explanations and smart elimination strategies.
- CRISPR-Cas9 and Homing Endonucleases (meganucleases) are major genome editing approaches
- Site-Directed Nuclease (SDN) technologies: Zinc-Finger Nucleases (ZFNs) and TALENs
- Guidelines for Safety Assessment of Genome Edited Plants, 2022 — notified by MoEFCC under EP Act 1986
- GEAC (Genetic Engineering Appraisal Committee) under MoEFCC — punitive action under EP Act 1986
- CAR-T Cell Therapy: T cells edited in lab to fight cancer; CD-19 is biomarker for B lymphocytes
- Indian Biological Data Center (IBDC) inaugurated at Faridabad — data stored on supercomputer Brahm (4 petabyte)
- National Gene Bank at NBPGR, Pusa (world's 2nd largest); National Animal Gene Bank at NBAGR, Karnal
- Indian Seed Vault at Chang La, Ladakh
Download the full PDF
Sherlocking Revision — S&T 2023 (Complete PDF)(2.5 MB)
Practice Science & Technology questions with the Sherlocking Method
Attempt UPSC-level MCQs with detailed explanations and smart elimination strategies.